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Proteintech
NPR3 Polyclonal Antibody
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产品信息
26706-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NPR3 Fusion Protein Ag19071 (48-378 aa encoded by BC131540)
偶联物
形式
Liquid
浓度
0.53 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LPPQKIEVL VLLPQDDSYL FSLTRVRPAI EYALRSVEGN GTGRRLLPPG TRFQVAYEDS DCGNRALFSL VDRVAAARGA KPDLILGPVC EYAAAPVARL ASHWDLPMLS AGALAAGFQH KDSEYSHLTR VAPAYAKMGE MMLALFRHHH WSRAALVYSD DKLERNCYFT LEGVHEVFQE EGLHTSIYSF DETKDLDLED IVRNIQASER VVIMCASSDT IRSIMLVAHR HGMTSGDYAF FNIELFNSSS YGDGSWKRGD KHDFEAKQAY SSLQTVTLLR TVKPEFEKFS MEVKSSVEKQ GLNMEDYVNM FVEGFHDAIL LYVLALHEVL RA (48-378 aa encoded by BC131540)
靶标信息
This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: A NPR-C; ANP-C; Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor 3; Atrial natriuretic peptide receptor type C; atrionatriuretic peptide receptor C; guanylate cyclase C; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
基因别名: ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPR3; NPRC
UniProt ID: (Human) P17342
Entrez Gene ID: (Human) 4883
skeletal system development
osteoclast proliferation
cAMP biosynthetic process
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
regulation of blood pressure
cyclic nucleotide biosynthetic process
cAMP-mediated signaling
pancreatic juice secretion
regulation of osteoblast proliferation
positive regulation of urine volume
phosphatidylinositol-mediated signaling
negative regulation of smooth muscle cell proliferation
positive regulation of nitric-oxide synthase activity
