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产品信息
PA5-50341
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Fusion protein corresponding to residues near the N terminal of human neuregulin 4 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2.4 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635794 |
产品详细信息
The antibody detects endogenous levels of total NRG4 protein.
靶标信息
The neuregulins, including NRG4, activate type-1 growth factor receptors to initiating cell-to-cell signaling through tyrosine phosphorylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: heregulin 4; Neuregulin-4; NRG-4; Pro-neuregulin-4, membrane-bound isoform; Pro-NRG4
基因别名: HRG4; NRG4
UniProt ID: (Human) Q8WWG1
Entrez Gene ID: (Human) 145957
分子生物学功能:
growth factor
MAPK cascade
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
intracellular signal transduction
ERBB2 signaling pathway
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
animal organ development
regulation of cell motility
