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Invitrogen
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: calmodulin-binding protein; NEUG(55-78); Neurogranin; neurogranin (protein kinase C substrate, RC3); Ng; postsynaptic spine 1; protein kinase C substrate; Protein kinase C substrate 7.5 kDa protein; RC3
基因别名: 0710001B06Rik; AI838505; hng; NG; NG/RC3; NRGN; Pss1; R75334; RC3
UniProt ID: (Human) Q92686, (Mouse) P60761, (Rat) Q04940
Entrez Gene ID: (Human) 4900, (Mouse) 64011, (Rat) 64356
