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Invitrogen
Hairy Cell Leukemia Monoclonal Antibody (DBA.44)
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产品信息
MA1-26274
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgM
分类
Monoclonal
类型
Antibody
克隆号
DBA.44
抗原
DEAU cell line established from a large cell lymphoma.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
tissue culture supernatant
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: Tonsil.
靶标信息
Hairy Cell Leukemia (HCL) is a rare form of mature B-cell cancer characterized by the presence of abnormal B-cells known as "hairy cells." These cells have a distinct genetic profile that plays a significant role in the diagnosis and management of the disease. HCL includes variants such as the hairy cell leukemia variant (HCL-V) and splenic diffuse red pulp lymphoma (SDRPL), which are often detected through specific immunophenotyping and genetic analyses. One critical aspect of these analyses involves the use of flow cytometry to detect lambda light chain restriction among B-cells displaying bright CD11c positivity. Advances in genetic profiling using techniques like clonal analysis with consensus primer polymerase chain reaction (PCR) for heavy chain genes have further refined diagnostic precision, distinguishing HCL from its variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
