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Invitrogen
NSUN4 Polyclonal Antibody
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产品信息
PA5-55735
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human NSUN4
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: FVNEAISHWE LQSEGGQSAA PSPASWACSP NLRCFTFDRG DISRFPPARP GSLGVMEYYL MDAASLLPVL ALGL
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 69%.
靶标信息
NSUN4 is a 5-methylcytosine rRNA methytransferase that is involved in mitochondiral ribosome assembly. More specifically NSUN4 is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA. This function is independent of MTREFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). NSUN4 is targeted to LSU by MTREFD2/MTERF4 and is involved in the final step in ribosome biogenesis to ensure that SSU and LSU are assembled.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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