Immunogen sequence: IVSNYMDFNE DGFLQGFKGQ LIHTYNKNSS VCENCGYFQQ LEGKTNVILL GDSIG
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233). [UniProt]
蛋白别名: 5'-nucleotidase, cytosolic III-like; 7-methylguanosine nucleotidase; 7-methylguanosine phosphate-specific 5'-nucleotidase; cN-III-like protein; Cytosolic 5'-nucleotidase 3B; Cytosolic 5'-nucleotidase III-like protein; N(7)-methylguanylate 5'-phosphatase
基因别名: cN-IIIB; NT5C3B; NT5C3L
UniProt ID: (Human) Q969T7
Entrez Gene ID: (Human) 115024