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产品信息
PA5-63399
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human NT5C3B
偶联物
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2644836
产品详细信息
Immunogen sequence: IVSNYMDFNE DGFLQGFKGQ LIHTYNKNSS VCENCGYFQQ LEGKTNVILL GDSIG
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.
靶标信息
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5'-nucleotidase, cytosolic III-like; 7-methylguanosine nucleotidase; 7-methylguanosine phosphate-specific 5'-nucleotidase; cN-III-like protein; Cytosolic 5'-nucleotidase 3B; Cytosolic 5'-nucleotidase III-like protein; N(7)-methylguanylate 5'-phosphatase
基因别名: cN-IIIB; NT5C3B; NT5C3L
UniProt ID: (Human) Q969T7
Entrez Gene ID: (Human) 115024
分子生物学功能:
esterase
hydrolase
metabolite interconversion enzyme
