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Invitrogen
NUCB2 Polyclonal Antibody
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NUCB2 Antibody (PA5-78096) in ICC/IF
NUCB2 Polyclonal Antibody detects NUCB2 protein at endoplasmic reticulum by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: NUCB2 protein stained by NUCB2 Polyclonal Antibody (Product # PA5-78096) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
产品信息
PA5-78096
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the C-terminus region of human NUCB2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Mouse (84%), Chicken (80%), Bovine (86%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA-binding protein NEFA; Epididymis secretory protein Li 109; Gastric cancer antigen Zg4; nesfatin 1; nesfatin-1; Nucleobindin-2; Nucleobindin-2/Nesfatin-1; nucleobinding 2; prepronefastin; Prepronesfatin
基因别名: HEL-S-109; NEFA; NUCB2; p54
UniProt ID: (Human) P80303, (Rat) Q9JI85
Entrez Gene ID: (Human) 4925, (Rat) 59295
