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Antibody detects endogenous levels of total NUP93.
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore. The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 93 kDa nucleoporin; CBP-interacting protein 4; Nuclear pore complex protein Nup93; nucleoporin 93kDa; Nucleoporin Nup93
基因别名: 2410008G02Rik; Cip4; KIAA0095; NIC96; NPHS12; NUP93
UniProt ID: (Human) Q8N1F7, (Mouse) Q8BJ71, (Rat) Q66HC5
Entrez Gene ID: (Human) 9688, (Mouse) 71805, (Rat) 291874