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Antibodies Inc
Navbeta3 Na+ Channel Monoclonal Antibody (N396/29), FL490
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产品信息
75-391-FL490
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
N396/29
抗原
Fusion protein amino acids 1-215 (full-length) of rat Navbeta3 (accession number Q9JK00) produced recombinantly in E. Coli.
偶联物
激发/发射光谱
491/515 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: brain and heart sodium channel beta 3 subunit; sodium channel beta 3 subunit; Sodium channel regulatory subunit beta-3; sodium channel subunit beta-3
基因别名: 1110001K16Rik; 4833414B02Rik; Scn3b; Scnb3
UniProt ID: (Mouse) Q8BHK2, (Rat) Q9JK00
Entrez Gene ID: (Mouse) 235281, (Rat) 245956
transport
ion transport
sodium ion transport
positive regulation of heart rate
positive regulation of sodium ion transport
regulation of ion transmembrane transport
sodium ion transmembrane transport
membrane depolarization
cardiac muscle contraction
regulation of atrial cardiac muscle cell membrane depolarization
regulation of ventricular cardiac muscle cell membrane depolarization
cardiac conduction
protein localization to plasma membrane
cardiac muscle cell action potential involved in contraction
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane depolarization during cardiac muscle cell action potential
atrial cardiac muscle cell action potential
SA node cell action potential
regulation of heart rate by cardiac conduction
regulation of sodium ion transmembrane transporter activity
nervous system development
sensory perception of pain
SA node cell to atrial cardiac muscle cell communication
