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Alomone Labs, LTD
Nectin-1/PVRL1 (extracellular) Polyclonal Antibody
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图: 1 / 5
Nectin-1/PVRL1 (extracellular) Antibody (ANR-051-200UL) in ICC/IF
Expression of Nectin-1 in rat PC12 cells - Cell surface detection of Nectin-1 in live intact rat PC12 pheochromocytoma cells. A. Extracellular staining of cells with Anti-Nectin-1/PVRL1 (extracellular) Antibody (#ANR-051), (1:100), followed by goat Anti-rabbit-AlexaFluor-594secondary Antibody (red). B. Live image of the cells. C. Merge of the two images.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
ANR-051-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)GKPPSVVSWETRLK, corresponding to amino acid residues 177-190 of human Nectin-1, Extracellular, N-terminus
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
规格
160 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD111; Herpes virus entry mediator C; Herpesvirus entry mediator C; Herpesvirus Ig-like receptor; HIgR; Nectin cell adhesion molecule 1; nectin); Nectin-1; nectin-1 alpha; nectin-1 delta; poliovirus receptor-related 1 (herpesvirus entry mediator C; poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin); Poliovirus receptor-related protein 1
基因别名: AI835281; AW549174; Cd111; HIgR; HVEC; nectin-1; NECTIN1; PRR; PRR1; PVRL1
UniProt ID: (Mouse) Q9JKF6
Entrez Gene ID: (Rat) 192183, (Mouse) 58235
lens morphogenesis in camera-type eye
desmosome organization
iron ion transport
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
axon guidance
single organismal cell-cell adhesion
viral entry into host cell
camera-type eye morphogenesis
regulation of synapse assembly
retina development in camera-type eye
enamel mineralization
cell adhesion
viral process
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