MUbio

Neurofilament 200 kD Monoclonal Antibody (RNF404)

Name: Neurofilament 200 kD Monoclonal Antibody (RNF404)
Brand: MUbio
SKU: MUB1306P

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说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

MUB1306P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:500

免疫组化（石蜡） (IHC (P))

1:50-1:100

免疫组化（冰冻） (IHC (F))

1:50-1:100

产品规格

种属反应

Bovine, Dog, Chicken, Guinea pig, Human, Mouse, Non-human primate, Sheep, Rabbit, Rat, Xenopus

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

RNF404

抗原

Neurofilament 200 kD

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

RNF404 reacts exclusively with the phosphorylated isoform of the 200 kD neurofilament protein.

The antibody may be stored at 4°C. For prolonged storage prepare appropriate aliquots and store at or below -20°C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at 4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.

靶标信息

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: 200 kDa neurofilament protein; heavy neurofilament protein; intermediate filament protein; NEF3; neurofilament; neurofilament 200kDa; Neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide L homeolog; neurofilament-H; NF 200 kD; NF-H; NHC

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基因别名: CMT2CC; KIAA0845; mKIAA0845; NEFH; NF-H; NF200; NFH; XELAEV_18007418mg

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UniProt ID: (Human) P12036, (Mouse) P19246