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Zeta
Neurofilament Recombinant Rabbit Monoclonal Antibody (ZR216), RAbMono™
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产品信息
Z2706RP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ZR216
抗原
Recombinant full-length human NEFL protein
偶联物
形式
Liquid
浓度
1 µg/mL
纯化类型
Protein A
保存液
tris with BSA, NP-40
内含物
<0.1% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
This product is diluted and in a ready-to-use formulation.
A recommended positive control tissue for this product is Brain, however positive controls are not limited to this tissue type.
靶标信息
Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 200 kDa neurofilament protein; NEF3; neurofilament; Neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; NF 200 kD; NF-H; NHC
基因别名: CMT2CC; KIAA0845; NEFH; NFH
UniProt ID: (Human) P12036
Entrez Gene ID: (Human) 4744
microtubule cytoskeleton organization
ovarian follicle atresia
axonogenesis
spinal cord development
hippocampus development
cerebral cortex development
cell projection assembly
axon regeneration
neurofilament bundle assembly
cellular response to oxidative stress
response to cocaine
peripheral nervous system neuron axonogenesis
axon development
cellular response to estradiol stimulus
regulation of organelle transport along microtubule
response to sodium arsenite
response to acrylamide
