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Neuromedin U Antibody (PA5-96566) in WB
Western blot analysis of Neuromedin U in extracts of various cell lines. Samples were incubated with Neuromedin U Polyclonal antibody (Product # PA5-96566) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
PA5-96566
产品规格
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
A synthetic peptide corresponding to amino acids 75-174 of human Neuromedin U.
Conjugate
Unconjugated
形式
Liquid
浓度
2.86 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2808368
Product Specific Information
Immunogen sequence: SNALEELCFM IMGMLPKPQE QDEKDNTKRF LFHYSKTQKL GKSNVVSSVV HPLLQLVPHL HERRMKRFRV DEEFQSPFAS QSRGYFLFRP RNGRRSAGFI
Positive samples: Mouse large intestine, Mouse stomach, Rat large intestine, Rat stomach; Cellular location: Secreted
Target Information
This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: Neuromedin precursor-related peptide 33; Neuromedin precursor-related peptide 36; Neuromedin-U; Neuromedin-U-23; Neuromedin-U-25; NmU 25; NmU-23; NmU-25; NURP33; NURP36; prepro-NMU
Gene Aliases: NMU
UniProt ID: (Human) P48645, (Rat) P12760, (Mouse) Q9QXK8
Entrez Gene ID: (Human) 10874, (Rat) 63887, (Mouse) 56183
gastric acid secretion
neuropeptide signaling pathway
photoperiodism
sensory perception of pain
eating behavior
positive regulation of smooth muscle contraction
positive regulation of hormone secretion
positive regulation of synaptic transmission
regulation of smooth muscle contraction
signal transduction
G-protein coupled receptor signaling pathway
digestion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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