Invitrogen

Neuropoietin Monoclonal Antibody (321525)

Name: Neuropoietin Monoclonal Antibody (321525)
Brand: Invitrogen
SKU: MA5-24044

查看其他2个Neuropoietin抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

Immunogen image

Immunogen Image Neuropoietin Monoclonal Antibody (321525)

产品信息

MA5-24044

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Rat / IgG1

分类

Monoclonal

类型

Antibody

克隆号

321525

抗原

E. coli-derived recombinant mouse Neuropoietin/NP Ala23-Ala204

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.5 mg/mL

纯化类型

Protein A/G

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2608238

产品详细信息

Reconstitute at 0.5 mg/mL in sterile PBS.

靶标信息

Neuropoietin is a newly identified member of the IL-6 cytokine family. Members of this family, including IL-6, IL-11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, and CNTF, display a four-helix bundle structure, and signal through gp130-containing receptor complexes. Neuropoietin, which is predominantly expressed in neuroepithelia during embryonic life, acts through a receptor complex formed of a CNTF receptor-alpha component, gp 130, and LIF receptor. Like CNTF, it promotes the survival of embryonic motor neurons, and could increase the proliferation of neural precursor cells in the presence of EGF and FGF-2. Interestingly, the human neuropoietin gene has evolved toward a pseudogene, suggesting that alternative signaling via CNTF is an effective compensatory pathway.

仅用于科研。不用于诊断过程。未经明确授权不得转售。