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This product can be used in direct ELISA.
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp781N13156; Neuroserpin; Peptidase inhibitor 12; PI-12; protease inhibitor 17; Serine protease inhibitor 17; Serpin I1
基因别名: AI837402; Ns; PI-12; PI12; Serpini1; Spi17
UniProt ID: (Mouse) O35684
Entrez Gene ID: (Mouse) 20713
分子生物学功能: protease inhibitor