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Alomone Labs, LTD
Noradrenaline Transporter (NET) (extracellular) Polyclonal Antibody
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Noradrenaline Transporter (NET) (extracellular) Antibody (AMT-002-200UL) in ICC/IF
Expression of Noradrenaline transporter (NET) in live intact rat PC12 cells - Cell surface detection of Noradrenaline transporter (NET) in live intact rat pheochromocytoma PC12 cells. Cells were stained with Anti-Noradrenaline Transporter (NET) (extracellular) Antibody (#AMT-002), (1:100), followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody (red). Cell nuclei (blue) were visualized using cell-per... View More
产品信息
AMT-002-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KLLNASVLGDHTKYSK, corresponding to amino acid residues 189-204 of mouse NET, 2nd extracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Norepinephrine Transporter [NET, or noradrenaline transporter (NAT)] is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NaCl-dependent norepinephrine transporter; NE transporter; NET; neurotransmitter transporter, noradrenal; noradrenaline; Norepinephrine transporter; Sodium-dependent noradrenaline transporter; solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; Solute carrier family 6 member 2; transmembrane region 4..26 transmembrane region 55..77 transmembrane region 105..123 transmembrane region 136..157
基因别名: NE-T; NET; Slc6a2; Slc6a5
UniProt ID: (Mouse) O55192
Entrez Gene ID: (Rat) 83511, (Mouse) 20538
