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Invitrogen
Nuclear Pore Complex Monoclonal Antibody (39C7)
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Nuclear Pore Complex Antibody (MA5-33097) in ICC/IF
Immunocytochemistry analysis of Nuclear Pore Complex in HeLa cells, stained with Nuclear Pore Complex monoclonal antibody (Product # MA5-33097) using a dilution of 1:100 (red) and rabbit Anti-Vimentin antibody using a dilution of 1:10,000 (green), the blue is DAPI staining nuclear DNA. The Anti-Nuclear Pore Complex antibody reveals strong granular labeling of the nuclei corresponding to the protein, while t... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-33097
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
39C7
抗原
Yeast nuclear preparations
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.25 mg/mL
规格
25 µg
保存液
tissue culture supernatant
内含物
10mM sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The nuclear pore complex (NPC) serves as the sole bidirectional gateway of macromolecules in and out of the nucleus. Each NPC consists of ~1,000 protein subunits, termed nucleoporins, and totals to a molecular mass of ~110 Mda. NPCs maintain the integrity of the nuclear compartment by preventing macromolecules from freely diffusing in or out of the nucleus. (Annu Rev Biochem, 2019. PMID 30883195)
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 107 kDa nucleoporin; 133 kDa nucleoporin; 153 kDa nucleoporin; 155 kDa nucleoporin; 160 kDa nucleoporin; 205 kDa nucleoporin; 214 kDa nucleoporin; 35 kDa nucleoporin; 50 kDa nucleoporin; 62 kDa nucleoporin; 85 kDa nucleoporin; 88 kDa nuclear pore complex protein; 88 kDa nucleoporin; 93 kDa nucleoporin; 98 kDa nucleoporin; alternatively spliced; CAN protein, putative oncogene; CBP-interacting protein 4; gene trap locus 1-13 protein; gene trap locus-13; GLFG-repeat containing nucleoporin; karyoporin; KIAA0023; KIAA0095; KIAA0225; mitotic phosphoprotein 44; nuclear envelope pore membrane protein POM 210; nuclear pore associated protein; nuclear pore associated protein 60 kDa; nuclear pore complex 1; nuclear pore complex protein 88; nuclear pore complex protein hnup153; nuclear pore complex protein Nup53; nuclear pore complex protein Nup98; nuclear pore glycoprotein 62; nuclear pore membrane protein 210; nuclear pore protein gp210; nuclear pore-associated protein 60L; nucleoporin; nucleoporin 107kDa; nucleoporin 133kD; nucleoporin 133kDa; nucleoporin 153kD; nucleoporin 153kDa; nucleoporin 155kD; nucleoporin 155kDa; nucleoporin 160kD; nucleoporin 160kDa; nucleoporin 205kDa; nucleoporin 210; nuclear pore membrane glycoprotein 210; nuclear pore membrane protein 210; nucleoporin 210kDa; nucleoporin 214kDa; nucleoporin 35kDa; nucleoporin 50 kDa; nucleoporin 50kD; nucleoporin 50kDa; nucleoporin 62kD; nucleoporin 62kDa; nucleoporin 85kDa; nucleoporin 88kDa; nucleoporin 93kDa; nucleoporin 96; nucleoporin 98kD; nucleoporin 98kDa; nucleoporin Nup107; nucleoporin Nup133; nucleoporin Nup153; nucleoporin Nup155; nucleoporin Nup160; nucleoporin Nup205; nucleoporin Nup210; nucleoporin Nup214; nucleoporin Nup35; nucleoporin Nup50; nucleoporin NUP53; nucleoporin Nup62; nucleoporin Nup75; nucleoporin Nup84; nucleoporin NUP85; nucleoporin Nup88; nucleoporin Nup93; nucleoporin Nup98; nucleoporin p62 homolog; nucleoprotein 50; Nucleoprotein 50kD; Nup155p; NUP50; NUP62; Nup98-Nup96; NUP98/PHF23 fusion 2 protein; p105; P140; pericentrin-1; pore membrane protein of 210 kDa; predicted protein of HQ1146; preimplantation protein 2; unnamed protein product
基因别名: 160kDa; 1700030K07Rik; 2310006I24Rik; 2410008G02Rik; 2810011M03Rik; 35kDa; 3830404O05Rik; 4732457F17; 5330402E05Rik; 9830001L10; ADIR2; ATFB15; B130015D15Rik; C7orf14; CAIN; CAN; D2H9S46E; D7Ertd649e; D930027M19Rik; FADS4; FROUNT; GAMOS7; GAMOS8; gp190; GP210; Gtl-13; Gtl1-13; Gtl13; hNUP133; HNUP153; IBSN; IIAE9; mermaid; mKIAA0197; mKIAA0225; mKIAA0791; MP-44; MP44; N153; N155; NIC96; NO44; NP44; Np62; NPAP60; NPAP60L; NPHS11; NPHS13; NPHS17; NPHS18; NPHS19; NUCZINK; NUP196; NUP53; Nup75; NUP84; NUP96; Nup98-96; Nupc1; ODG6; ODG6; GAMOS7; p62; Pcnt1; POM210; Prei2; RGD1304977; Rtp60; SNDI
UniProt ID: (Human) P57740, (Human) Q8WUM0, (Human) P49790, (Human) O75694, (Human) Q12769, (Human) Q92621, (Human) Q8TEM1, (Human) P35658, (Human) Q8NFH5, (Human) Q9UKX7, (Human) P37198, (Human) Q9BW27, (Human) Q99567, (Human) Q8N1F7, (Human) P52948, (Mouse) Q8BH74, (Mouse) Q8R0G9, (Mouse) E9Q3G8, (Rat) P37199, (Mouse) Q99P88, (Mouse) Q9Z0W3, (Rat) P11654, (Mouse) Q9QY81, (Mouse) Q80U93, (Rat) Q68FY1, (Mouse) Q8R4R6, (Rat) O08587, (Mouse) Q9JIH2, (Rat) P17955, (Mouse) Q63850, (Rat) Q4QQS8, (Mouse) Q8R480, (Mouse) Q8CEC0, (Rat) O08658, (Mouse) Q8BJ71, (Rat) Q66HC5, (Rat) P49793, (Mouse) Q6PFD9
Entrez Gene ID: (Human) 57122, (Human) 55746, (Human) 9972, (Human) 9631, (Human) 23279, (Human) 23165, (Human) 23225, (Human) 8021, (Human) 129401, (Human) 10762, (Human) 23636, (Human) 79902, (Human) 4927, (Human) 9688, (Human) 4928, (Rat) 116555, (Mouse) 103468, (Mouse) 234865, (Rat) 292085, (Mouse) 218210, (Rat) 25281, (Rat) 117021, (Mouse) 170762, (Mouse) 59015, (Rat) 311182, (Mouse) 70699, (Rat) 362335, (Rat) 58958, (Mouse) 54563, (Rat) 296634, (Mouse) 227720, (Rat) 295692, (Mouse) 69482, (Rat) 25497, (Mouse) 18141, (Rat) 65274, (Mouse) 18226, (Rat) 287830, (Mouse) 445007, (Mouse) 19069, (Rat) 113929, (Mouse) 71805, (Rat) 291874, (Rat) 81738, (Mouse) 269966
protein binding
structural constituent of nuclear pore
nuclear localization sequence binding
identical protein binding
protein anchor
molecular condensate scaffold activity
nuclear export signal receptor activity
nucleic acid binding
phospholipid binding
chromatin binding
receptor signaling complex scaffold activity
Hsp70 protein binding
SH2 domain binding
ubiquitin binding
PTB domain binding
Hsp90 protein binding
transcription coactivator activity
RNA binding
mRNA binding
peptide binding
promoter-specific chromatin binding
double-stranded DNA binding
zinc ion binding
small GTPase binding
kinesin binding
macromolecular complex binding
thyroid hormone receptor binding
CCR2 chemokine receptor binding
nucleocytoplasmic transport
protein-containing complex assembly
posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
mRNA export from nucleus
protein import into nucleus
biological_process
female gonad development
nuclear pore complex assembly
nephron development
neural tube formation
nuclear envelope organization
poly(A)+ mRNA export from nucleus
positive regulation of SMAD protein import into nucleus
nuclear pore organization
ribosomal large subunit export from nucleus
ribosomal small subunit export from nucleus
chemotaxis
lamellipodium assembly
positive regulation of transcription, DNA-templated
macrophage chemotaxis
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
neural tube development
neurogenesis
paraxial mesoderm development
animal organ development
system development
somite development
RNA export from nucleus
protein targeting to nuclear inner membrane
protein localization to nucleus
production of miRNAs involved in gene silencing by miRNA
atrial cardiac muscle cell action potential
mitotic metaphase plate congression
centrosome cycle
mitotic centrosome separation
cell surface receptor signaling pathway
negative regulation of cell proliferation
regulation of signal transduction
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of apoptotic process
negative regulation of programmed cell death
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of mitotic nuclear division
regulation of Ras protein signal transduction
negative regulation of Ras protein signal transduction
positive regulation of centriole replication
regulation of mitotic spindle organization
centriole assembly
positive regulation of mitotic cytokinetic process
positive regulation of protein localization to centrosome
NLS-bearing protein import into nucleus
cellular response to leukemia inhibitory factor
negative regulation of RNA export from nucleus
amyloid fibril formation
spermatogenesis
regulation of protein import into nucleus
negative regulation of MAP kinase activity
cellular senescence
protein export from nucleus
intracellular protein transport
regulation of nucleocytoplasmic transport
regulation of cell cycle
telomere tethering at nuclear periphery
positive regulation of mRNA splicing, via spliceosome
cytokine-mediated signaling pathway
cell migration
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