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Invitrogen
O-acetyl GD3 Monoclonal Antibody (D1.1)
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Additional Information:
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
37-9100
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human,
Rat
宿主/亚型
Mouse
/ IgM
分类
Monoclonal
类型
Antibody
克隆号
D1.1
抗原
B49 cells
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
保存条件
-20°C
运输条件
Wet ice
RRID
靶标信息
O-acetyl GD3 is a naturally occurring modification of GD3 (O-acetylation) that can reverse its apoptotic effects, suggesting a way for cells to avoid the fate of Gd3-induced apoptosis. Glycosphingolipids (GSLs) are amphipathic molecules with a polar glycan chain as a head group and a hydrophobic sphingosine-containing ceramide tail, which is typically embedded in the outer leaflet of the plasma membrane. A GSL called Gd3 has recently been shown to be involved in Fas-mediated apoptosis in hematopoietic cells, causing the loss of mitochondrial potential and the release of apoptotic factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
