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Invitrogen
OAS1 Polyclonal Antibody
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产品信息
PA5150069
产品规格
种属反应
Rat
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
Recombinant 2',5'-Oligoadenylate Synthetase 1 (OAS1) (Ala139-Leu358)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (2-5')oligo(A) synthase 1; (2-5')oligo(A) synthase 1A; (2-5')oligo(A) synthetase 1; 2',5'-oligoadenylate synthetase 1, 40/46kDa; 2'-5' oligoadenylate synthetase 1G; 2'-5'-oligoadenylate synthase 1; 2'-5'-oligoadenylate synthase 1A; 2'-5'-oligoadenylate synthetase 1; 2-5A synthase 1; 2-5A synthase 1A; 2-5A synthetase 1; 25 oligoadenylate synthetase; IFI 4; IFI4; OAS 1
基因别名: Oas1; Oas1a; Oas1g
UniProt ID: (Rat) Q05961
Entrez Gene ID: (Rat) 192281
glucose metabolic process
purine nucleotide biosynthetic process
immune response
metabolic process
response to virus
cellular response to interferon-alpha
glucose homeostasis
negative regulation of viral genome replication
innate immune response
negative regulation of viral process
protein oligomerization
defense response to virus
regulation of ribonuclease activity
