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Proteintech
OAS3 Polyclonal Antibody
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产品信息
21915-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
OAS3 Fusion Protein Ag16150 (1-350 aa encoded by BC113746)
偶联物
形式
Liquid
浓度
0.39 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDLYSTPAA ALDRFVARRL QPRKEFVEKA RRALGALAAA LRERGGRLGA AAPRVLKTVK GGSSGRGTAL KGGCDSELVI FLDCFKSYVD QRARRAEILS EMRASLESWW QNPVPGLRLT FPEQSVPGAL QFRLTSVDLE DWMDVSLVPA FNVLGQAGSG VKPKPQVYST LLNSGCQGGE HAACFTELRR NFVNIRPAKL KNLILLVKHW YHQVCLQGLW KETLPPVYAL ELLTIFAWEQ GCKKDAFSLA EGLRTVLGLI QQHQHLCVFW TVNYGFEDPA VGQFLQRQLK RPRPVILDPA DPTWDLGNGA AWHWDLLAQE AASCYDHPCF LRGMGDPVQS WKGPGLPRAG C (1-350 aa encoded by BC113746)
靶标信息
OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: (2-5')oligo(A) synthase 3; (2-5')oligo(A) synthetase 3; 2'-5'-oligoadenylate synthase 3; 2'-5'-oligoadenylate synthetase 3, 100kDa; 2'-5'oligoadenylate synthetase p100; 2-5A synthase 3; 2-5A synthetase 3; p100 OAS; p100OAS
基因别名: OAS3; P/OKcl.4; p100; p100OAS
UniProt ID: (Human) Q9Y6K5
Entrez Gene ID: (Human) 4940
