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Proteintech
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MTTETFVKD IKPGLKNLNL IFIVLETGRV TKTKDGHEVR TCKVADKTGS INISVWDDVG NLIQPGDIIR LTKGYASVFK GCLTLYTGRG GDLQKIGEFC MVYSEVPNFS EPNPEYSTQQ APNKAVQNDS NPSASQPTTG PSAASPASEN QNGNGLSAPP GPGGGPHPPH TPSHPPSTRI TRSQPNHTPA GPPGPSSNPV SNGKETRRSS KR (1-211 aa encoded by BC001079)
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Nucleic acid-binding protein 2; oligonucleotide/oligosaccharide-binding fold containing 2B; Oligonucleotide/oligosaccharide-binding fold-containing protein 2B; Sensor of single-strand DNA complex subunit B1; Sensor of ssDNA subunit B1; Single-stranded DNA-binding protein 1; SOSS complex subunit B1; SOSS-B1
基因别名: 2610036N15Rik; Nabp2; Obfc2b; RGD1308158; Ssb1
UniProt ID: (Mouse) Q8R2Y9, (Rat) Q3SWT1
Entrez Gene ID: (Mouse) 69917, (Rat) 362813