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Proteintech
OCT1 Polyclonal Antibody
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产品信息
10387-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Pig
已发表种属
Human,
Mouse,
Pig,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
OCT1 Fusion Protein Ag0586 (379-659 aa encoded by BC003571)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RRKKRTSIE TNIRVALEKS FLENQKPTSE EITMIADQLN MEKEVIRVWF CNRRQKEKRI NPPSSGGTSS SPIKAIFPSP TSLVATTPSL VTSSAATTLT VSPVLPLTSA AVTNLSVTGT SDTTSNNTAT VISTAPPASS AVTSPSLSPS PSASASTSEA SSASETSTTQ TTSTPLSSPL GTSQVMVTAS GLQTAAAAAL QGAAQLPANA SLAAMAAAAG LNPSLMAPSQ FAAGGALLSL NPGTLSGALS PALMSNSTLA TIQALASGGS LPITSLDATG NL (379-659 aa encoded by BC003571)
靶标信息
OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: NF-A1; Oct-1; octamer binding protein 1; Octamer-binding protein 1; Octamer-binding transcription factor 1; Octamer-binding transcription factor-1; OTF-1; POU domain, class 2, transcription factor 1
基因别名: oct-1B; OCT1; OTF1; POU2F1
UniProt ID: (Human) P14859, (Pig) Q29076
Entrez Gene ID: (Human) 5451, (Pig) 397501
