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Proteintech
OLFM3 Polyclonal Antibody
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产品信息
12596-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
OLFM3 Fusion Protein Ag3207 (179-478 aa encoded by BC022531)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: NLSAVLTGI QEEIGAYDYE ELHQRVLSLE TRLRDCMKKL TCGKLMKITG PVTVKTSGTR FGAWMTDPLA SEKNNRVWYM DSYTNNKIVR EYKSIADFVS GAESRTYNLP FKWAGTNHVV YNGSLYFNKY QSNIIIKYSF DMGRVLAQRS LEYAGFHNVY PYTWGGFSDI DLMADEIGLW AVYATNQNAG NIVISQLNQD TLEVMKSWST GYPKRSAGES FMICGTLYVT NSHLTGAKVY YSYSTKTSTY EYTDIPFHNQ YFHISMLDYN ARDRALCAWN NGHQVLFNVT LFHIIKTEDD T (179-478 aa encoded by BC022531)
靶标信息
OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Noelin-3; olfactomedin related ER localized protein 3; Olfactomedin-3; Optimedin
基因别名: B230206G02Rik; NOE3; NOELIN3; OLFM3; OPTIMEDIN; UNQ1924/PRO4399
UniProt ID: (Human) Q96PB7, (Mouse) P63056
Entrez Gene ID: (Human) 118427, (Mouse) 229759
