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Product Details
PA5-50866
产品规格
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Fusion protein corresponding to residues near the C terminal of human olfactomedin 3
Conjugate
Unconjugated
形式
Liquid
浓度
1.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
RRID
AB_2636318
Product Specific Information
The antibody detects endogenous levels of total OLFM3 protein.
Target Information
OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: Noelin-3; olfactomedin related ER localized protein 3; Olfactomedin-3; Optimedin
Gene Aliases: B230206G02Rik; NOE3; NOELIN3; OLFM3; OPTIMEDIN; UNQ1924/PRO4399
UniProt ID: (Human) Q96PB7, (Mouse) Q8R4K4
Entrez Gene ID: (Human) 118427, (Mouse) 229759
Molecular Function:
structural protein
Performance Guarantee
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