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Invitrogen
ONECUT2 Polyclonal Antibody
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产品信息
PA5-114121
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human ONECUT2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LQEPEFQRMS ALRLAACKRK EQEPNKDRNN SQKKSRLVFT DLQRRTLFAI
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
靶标信息
ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hepatocyte nuclear factor 6-beta; HNF-6-beta; HNF-6B; OC-2; One cut domain family member 2; one cut domain, family member 2; One cut homeobox 2; onecut 2; ONECUT-2 homeodomain transcription factor; Transcription factor ONECUT-2
基因别名: HNF6B; OC-2; OC2; ONECUT2
UniProt ID: (Human) O95948
Entrez Gene ID: (Human) 9480
liver development
regulation of cell-matrix adhesion
epithelial cell development
transcription from RNA polymerase II promoter
organ morphogenesis
cell differentiation
positive regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
endocrine pancreas development
cilium assembly
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
peripheral nervous system neuron development
