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Invitrogen
ONECUT2 Monoclonal Antibody (606014)
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ONECUT2 Antibody (MA5-24275) in ICC/IF
Immunocytochemistry analysis of ONECUT2 was detected in immersion fixed HepG2 human hepatocellular carcinoma cell line. The cells were labeled with ONECUT2 Mouse Monoclonal Antibody (Product # MA5-24275) using a dilution of 10 µg/mL for 3 hours at room temperature. Cells were stained using the Northern-Lights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red) counterstained with DAPI (blue). Specific staining was localized to nuclei.
产品信息
MA5-24275
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
606014
抗原
E. coli-derived recombinant human ONECUT2/OC-2 Gln185-Thr326
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
No cross-reactivity with recombinant human ONECUT is observed.
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
靶标信息
ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hepatocyte nuclear factor 6-beta; HNF-6-beta; HNF-6B; OC-2; One cut domain family member 2; one cut domain, family member 2; One cut homeobox 2; onecut 2; ONECUT-2 homeodomain transcription factor; Transcription factor ONECUT-2
基因别名: HNF6B; OC-2; OC2; ONECUT2
UniProt ID: (Human) O95948
Entrez Gene ID: (Human) 9480
liver development
regulation of cell-matrix adhesion
epithelial cell development
transcription from RNA polymerase II promoter
organ morphogenesis
cell differentiation
positive regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
endocrine pancreas development
cilium assembly
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
peripheral nervous system neuron development
