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Proteintech
ORAI3 Polyclonal Antibody
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产品信息
25766-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ORAI3 Fusion Protein Ag22513 (1-100 aa encoded by BC006126)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2. Larger molecular weight bands are sometimes seen in SDS-PAGE; these may represent post-translationally modified ORAI 3.
Immunogen sequence: MKGGEGDAG EQAPLNPEGE SPAGSATYRE FVHRGYLDLM GASQHSLRAL SWRRLYLSRA KLKASSRTSA LLSGFAMVAM VEVQLESDHE YPPGLLVAFS A (1-100 aa encoded by BC006126)
靶标信息
ORAI3 is a protein coding gene that is involved in calcium signaling and regulation of calcium homeostasis. It is a member of the ORAI family of proteins that form calcium release-activated calcium (CRAC) channels in the plasma membrane of cells. These channels are activated by depletion of calcium from the endoplasmic reticulum, leading to an influx of calcium ions into the cytoplasm. ORAI3 has been implicated in a variety of physiological processes, including T-cell activation, muscle contraction, and neurotransmitter release. Dysregulation of ORAI3 expression or function has been associated with various diseases, including immune disorders, cancer, and cardiovascular disease
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: calcium release-activated calcium channel 3; Protein orai-3; Transmembrane protein 142C
基因别名: 9930124N15; BC061259; ORAI3; TMEM142C
UniProt ID: (Human) Q9BRQ5, (Mouse) Q6P8G8
Entrez Gene ID: (Human) 93129, (Mouse) 269999
