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This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Protein Aliases: homolog of latheo, Drosophila; IMAGE50150; Origin recognition complex subunit 3; Origin recognition complex subunit Latheo; origin recognition complex, subunit 3 honolog; OTTHUMP00000040611; RP3-486L4.1
Gene Aliases: LAT; LATHEO; ORC3; ORC3L
UniProt ID: (Human) Q9UBD5
Entrez Gene ID: (Human) 23595
Molecular Function:
DNA metabolism protein
nucleic acid metabolism protein
replication origin binding protein
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