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ORC3 Antibody (PA5-17949) in IHC (P)
Immunohistochemical analysis of ORC3 in paraffin embedded human cortex using a ORC3 polyclonal antibody (Product #PA5-17949) at a concentration of 3.75 µg/mL. Steamed antigen retrieval was performed with pH 6 buffered citrate. Samples were then stained with alkaline phosphatase.
Product Details
PA5-17949
产品规格
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Synthetic peptide sequence (QKTDHVARLTWGGC) corresponding to the C-terminus amino acids of ORC3L
Conjugate
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_10977077
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
Target Information
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: homolog of latheo, Drosophila; IMAGE50150; Origin recognition complex subunit 3; Origin recognition complex subunit Latheo; origin recognition complex, subunit 3 honolog; OTTHUMP00000040611; RP3-486L4.1
Gene Aliases: LAT; LATHEO; ORC3; ORC3L
UniProt ID: (Human) Q9UBD5
Entrez Gene ID: (Human) 23595
Molecular Function:
DNA metabolism protein
nucleic acid metabolism protein
replication origin binding protein
Performance Guarantee
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