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Product Details
PA5-17948
产品规格
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Synthetic peptide sequence (ENAASAQKATAE) corresponding to the C-terminus amino acids of ORC6L
Conjugate
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_10987490
Target Information
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: ORC 6; Origin recognition complex subunit 6
Gene Aliases: ORC6; ORC6L
UniProt ID: (Human) Q9Y5N6
Entrez Gene ID: (Human) 23594
Molecular Function:
replication origin binding protein
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