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Proteintech
OS9 Polyclonal Antibody
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产品信息
10061-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
OS9 Fusion Protein Ag0106 (125-435 aa encoded by BC000532)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody can recognize all three isoforms of OS-9.
Immunogen sequence: GRHIQQYHM EDSEIKGEVL YLGYYQSAFD WDDETAKASK QHRLKRYHSQ TYGNGSKCDL NGRPREAEVR FLCDEGAGIS GDYIDRVDEP LSCSYVLTIR TPRLCPHPLL RPPPSAAPQA ILCHPSLQPE EYMAYVQRQA DSKQYGDKII EELQDLGPQV WSETKSGVAP QKMAGASPTK DDSKDSDFWK MLNEPEDQAP GGEEVPAEEQ DPSPEAADSA SGAPNDFQNN VQVKVIRSPA DLIRFIEELK GGTKKGKPNI GQEQPVDDAA EVPQREPEKE RGDPERQREM EEEEDEDEDE DEDEDERQLL GE (125-435 aa encoded by BC000532)
靶标信息
OS9 is an ER glycoprotein found in the intralumenal level and highly expressed in tumor tissue. The OS9 gene is transcriptionally induced upon activation of the Ire1/Xbp1 ER-stress pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Amplified in osteosarcoma 9; endoplasmic reticulum lectin 2; erlectin 2; osteosarcoma amplified 9, endoplasmic reticulum associated protein; osteosarcoma amplified 9, endoplasmic reticulum lectin; Protein OS-9
基因别名: ERLEC2; OS-9; OS9
UniProt ID: (Human) Q13438
Entrez Gene ID: (Human) 10956
protein targeting
protein retention in ER lumen
protein ubiquitination
ER-associated ubiquitin-dependent protein catabolic process
response to endoplasmic reticulum stress
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of retrograde protein transport, ER to cytosol
endoplasmic reticulum mannose trimming
