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Invitrogen
OVOL2 Polyclonal Antibody
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图: 1 / 11
OVOL2 Antibody (PA5-115700) in ICC/IF
Immunocytochemistry analysis of OVOL2 in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115700). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115700
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human OVOL2(Accession Q9BRP0), corresponding to amino acid residues V200-L250.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total OVOL2.
靶标信息
DNA-binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. Probably acts as a transcription regulator.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hOvo2; MOVO-B zinc finger protein; MOVO-C zinc finger protein; mOvo2; OVO homolog-like 2; ovo-like 2; Transcription factor Ovo-like 2; Zinc finger OVO2; Zinc finger protein 339; Zinc finger protein mOVO
基因别名: 1700108N11Rik; 1810007D21Rik; M-OVO; M-OVO-A; M-OVO-B; MOVO; movo2; Ovo2; OVOL2; Zfp339; ZNF339
UniProt ID: (Mouse) Q8CIV7
Entrez Gene ID: (Rat) 296201, (Mouse) 107586
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription regulatory region DNA binding
metal ion binding
nucleic acid binding
transcription factor activity, sequence-specific DNA binding
angiogenesis
neural crest cell migration
neural fold formation
heart looping
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
heart development
negative regulation of cell proliferation
epidermis development
epidermal cell differentiation
dorsal/ventral pattern formation
negative regulation of epithelial to mesenchymal transition
regulation of keratinocyte proliferation
negative regulation of transcription by competitive promoter binding
negative regulation of keratinocyte differentiation
positive regulation of keratinocyte differentiation
negative regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
embryonic digestive tract morphogenesis
regulation of cell cycle
endocardium formation
heart trabecula formation
labyrinthine layer blood vessel development
negative regulation of stem cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
positive regulation of transcription from RNA polymerase II promoter
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