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Invitrogen
Omburtamab Recombinant Mouse Monoclonal Antibody
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产品信息
MA5-42216
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human CD276/B7-H3/B7RP-2
偶联物
形式
Liquid
浓度
3.19 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.5
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Omburtamab is a monoclonal antibody that targets the B7-H3 antigen expressed in a variety of human solid tumors. Omburtamab (alias: 8H9, former name: Burtomab) is a monoclonal antibody that is linked to a radioisotope and can bind to the B7-H3 antigen on the surface of neuroblastoma cells. It is injected directly into the cerebrospinal fluid to bypass the blood-brain barrier and accurately target neuroblastoma in the central nervous system to avoid damage to other tissues (such as learning disabilities and developmental delays often caused by conventional radiotherapy outside the brain).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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