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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
酶联免疫吸附实验 (ELISA) |
5-10 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Chemical |
宿主/亚型 |
Sheep / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Oxycodone(N)-BSA |
偶联物 |
Unconjugated |
形式 |
Liquid |
纯化类型 |
purified |
保存液 |
PBS |
内含物 |
0.09% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_1090592 |
PA1-75335 specifically detects Oxycodone.
PA1-75335 has been successfully used in ELISA applications.
The PA1-75335 immunogen is Oxycodone(N)-BSA.
Oxycodone is a semi-synthetic, morphine-like opioid alkaloid with analgesic activity. Oxycodone exerts its analgesic activity by binding to the mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opioids. Binding of the opiate receptor stimulates the exchange of GTP for GDP on the G-protein complex and inhibits adenylate cyclase, thereby preventing cAMP production. Subsequently, the release of nociceptive neurotransmitters, such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, and noradrenaline, is inhibited. Oxycodone also inhibits the release of vasopressin, somatostatin, insulin, and glucagon. In addition, oxycodone closes N-type voltage-gated calcium channels and opens G-protein-coupled inwardly rectifying potassium channels resulting in hyperpolarization and reduction of neuronal excitability. [National Center for Biotechnology Information. PubChem Compound Database; CID=5284603].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C18H21NO4; Dihydrohydroxycodeinone; Dihydrone; Dihydroxycodeinone; Oxycodeinone; Oxycontin
