Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA1-75335
产品规格
Species Reactivity
Chemical
Host/Isotype
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Oxycodone(N)-BSA
Conjugate
Unconjugated
形式
Liquid
纯化类型
purified
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_1090592
Product Specific Information
PA1-75335 specifically detects Oxycodone.
PA1-75335 has been successfully used in ELISA applications.
The PA1-75335 immunogen is Oxycodone(N)-BSA.
Target Information
Oxycodone is a semi-synthetic, morphine-like opioid alkaloid with analgesic activity. Oxycodone exerts its analgesic activity by binding to the mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opioids. Binding of the opiate receptor stimulates the exchange of GTP for GDP on the G-protein complex and inhibits adenylate cyclase, thereby preventing cAMP production. Subsequently, the release of nociceptive neurotransmitters, such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, and noradrenaline, is inhibited. Oxycodone also inhibits the release of vasopressin, somatostatin, insulin, and glucagon. In addition, oxycodone closes N-type voltage-gated calcium channels and opens G-protein-coupled inwardly rectifying potassium channels resulting in hyperpolarization and reduction of neuronal excitability. [National Center for Biotechnology Information. PubChem Compound Database; CID=5284603].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: C18H21NO4; Dihydrohydroxycodeinone; Dihydrone; Dihydroxycodeinone; Oxycodeinone; Oxycontin
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support