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Proteintech
P3H2 Polyclonal Antibody
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产品信息
15723-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
P3H2 Fusion Protein Ag8444 (179-527 aa encoded by BC005029)
偶联物
形式
Liquid
浓度
0.14 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: ASIEAREDL TMFVKRHKLE SELIKSAAEG LGFSYTEPNY WIRYGGRQDE NRVPSGVNVE GAEVHGFSMG KKLSPKIDRD LREGGPLLYE NITFVYNSEQ LNGTQRVLLD NVLSEEQCRE LHSVASGIML VGDGYRGKTS PHTPNEKFEG ATVLKALKSG YEGRVPLKSA RLFYDISEKA RRIVESYFML NSTLYFSYTH MVCRTALSGQ QDRRNDLSHP IHADNCLLDP EANECWKEPP AYTFRDYSAL LYMNDDFEGG EFIFTEMDAK TVTASIKPKC GRMISFSSGG ENPHGVKAVT KGKRCAVALW FTLDPLYREL ERIQADEVIA ILDQEQQGKH ELNINPKDEL (179-527 aa encoded by BC005029)
靶标信息
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: leprecan-like 1; Leprecan-like protein 1; myxoid liposarcoma associated protein 4; Myxoid liposarcoma-associated protein 4; procollagen-proline 3-dioxygenase 2; Prolyl 3-hydroxylase 2; prolyl 3-hydroxylase 3
基因别名: 4832416N06; AW553532; LEPREL1; MCVD; MLAT4; P3H2
UniProt ID: (Human) Q8IVL5, (Mouse) Q8CG71
Entrez Gene ID: (Human) 55214, (Mouse) 210530
iron ion binding
procollagen-proline 3-dioxygenase activity
L-ascorbic acid binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
metal ion binding
dioxygenase activity
extracellular matrix glycoprotein
