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Proteintech
PABPC1/PABP Polyclonal Antibody
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产品信息
10970-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PABPC1,PABP Fusion Protein Ag1422 (287-636 aa encoded by BC015958)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RITRYQGVN LYVKNLDDGI DDERLRKEFS PFGTITSAKV MMEGGRSKGF GFVCFSSPEE ATKAVTEMNG RIVATKPLYV ALAQRKEERQ AHLTNQYMQR MASVRAVPNP VINPYQPAPP SGYFMAAIPQ TQNRAAYYPP SQIAQLRPSP RWTAQGARPH PFQNMPGAIR PAAPRPPFST MRPASSQVPR VMSTQRVANT STQTMGPRPA AAAAAATPAV RTVPQYKYAA GVRNPQQHLN AQPQVTMQQP AVHVQGQEPL TASMLASAPP QEQKQMLGER LFPLIQAMHP TLAGKITGML LEIDNSELLH MLESPESLRS KVDEAVAVLQ AHQAKEAAQK AVNSATGVPT V (287-636 aa encoded by BC015958)
靶标信息
The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4), and PABP3 (PABPC3). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: PABP 1; PABP-1; poly A binding protein 1; poly(A) binding protein, cytoplasmic 1; poly(A) binding protein, cytoplasmic 2; poly(A)-binding protein 1; Polyadenylate-binding protein 1
基因别名: ePAB; PAB1; PABP; PABP1; PABPC1; PABPC2; PabpI; PABPL1
UniProt ID: (Human) P11940, (Rat) Q9EPH8, (Mouse) P29341
Entrez Gene ID: (Human) 26986, (Rat) 171350, (Mouse) 18458
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
mRNA processing
RNA splicing
gene silencing by RNA
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
nuclear-transcribed mRNA poly(A) tail shortening
mRNA splicing, via spliceosome
mRNA polyadenylation
translational initiation
regulation of mRNA stability
positive regulation of viral genome replication
positive regulation of translation
mRNA stabilization
