图: 1 / 5
Positive Samples: HeLa, SH-SY5Y, U-87MG; Cellular Location: Cell membrane, Multi-pass membrane protein
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Alternative splicing of two exons of this gene generates four major splice variants, but their full-length nature has not been determined. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
蛋白别名: ADCYAP1 R1; ADCYAP1R 1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; adenylate cyclase activating polypeptide 1 type 1 receptor; PAC 1; PAC1 receptor; Pac1 receptors; PACAP R 1; PACAP Receptor; PACAP receptor 1; PACAP type I receptor; PACAP type IA receptor; PACAP-R-1; PACAP-R-1A; PACAP-R1; PACAP/VIP receptors; PACAP1 R; PACAP1 receptor; pituitary adenylate cyclase activating polypeptide 1 receptor (1); pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; pituitary adenylate cyclase activating polypeptide receptor; Pituitary adenylate cyclase-activating polypeptide type I receptor; pituitary adenylate cyclase-activating polypeptide type IA receptor; pvr1
基因别名: 2900024I10Rik; ADCYAP1R1; AI846590; PAC1; PAC1-R; PAC1R; PACAP-R1; PACAP-R1A; PACAP1-R; PACAPR; PACAPR1; PACAPR1A; PACAPRI
分子生物学功能: transmembrane signal receptor