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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:10,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:100-1:1,000 | 查看1篇已发表文章 1篇已发表文章 |
免疫细胞化学 (ICC/IF) |
1:100-1:1,000 | 查看1篇已发表文章 1篇已发表文章 |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
已发表种属 |
Human, Rhesus monkey |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fragment corresponding to a region within amino acids 326 and 611 of PAD4 (Uniprot ID#Q9UM07) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.44 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7, with 1% BSA, 20% glycerol |
内含物 |
0.025% Proclin 300 |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_11155990 |
Recommended positive controls: PAD4-transfected 293T.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HL-60 PAD; PAD type IV; PADI-H protein; peptidyl arginine deiminase, type IV; peptidyl arginine deiminase, type V; Peptidylarginine deiminase IV; Protein-arginine deiminase type IV; Protein-arginine deiminase type-4
基因别名: PAD; PAD4; PADI4; PADI5; PDI4; PDI5
UniProt ID: (Human) Q9UM07, (Mouse) Q9Z183
Entrez Gene ID: (Human) 23569, (Mouse) 18602
