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Bioss
PAF Polyclonal Antibody
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产品信息
BS-1119R
应用
建议稀释比
已发表文章
产品规格
种属反应
Chemical
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated PAF.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Platelet Activating Factor (PAF) is a potent phospholipid mediator involved in various biological processes, including inflammation, thrombosis, and allergic reactions. PAF is synthesized by various cell types, including platelets, endothelial cells, and leukocytes. It exerts its effects by binding to the PAF receptor (PAFR), a G-protein coupled receptor, triggering a cascade of intracellular signaling pathways.PAF plays a critical role in the regulation of platelet aggregation, vascular permeability, and leukocyte activation. It is implicated in numerous pathological conditions, such as asthma, sepsis, cardiovascular diseases, and cancer. Due to its significant role in inflammation and immune responses, PAF is considered a valuable target for therapeutic interventions aimed at modulating its activity to treat associated diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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