Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
PAF1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
15441-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PAF1 Fusion Protein Ag7212 (166-531 aa encoded by BC000017)
偶联物
形式
Liquid
浓度
0.24 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
The MW of this protein is 80 kDa, and this antibody specifically recognizes the 80 kDa protein.
Immunogen sequence: EEIYKDRDS QITAIEKTFE DAQKSISQHY SKPRVTPVEV MPVFPDFKMW INPCAQVIFD SDPAPKDTSG AAALEMMSQA MIRGMMDEEG NQFVAYFLPV EETLKKRKRD QEEEMDYAPD DVYDYKIARE YNWNVKNKAS KGYEENYFFI FREGDGVYYN ELETRVRLSK RRAKAGVQSG TNALLVVKHR DMNEKELEAQ EARKAQLENH EPEEEEEEEM ETEEKEAGGS DEEQEKGSSS EKEGSEDEHS GSESEREEGD RDEASDKSGS GEDESSEDEA RAARDKEEIF GSDADSEDDA DSDDEDRGQA QGGSDNDSDS GSNGGGQRSR SHSRSASPFP SGSEHSAQED GSEAAASDSS EADSDSD (166-531 aa encoded by BC000017 )
靶标信息
This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hPAF1; Paf1, RNA polymerase II associated factor, homolog; Pancreatic differentiation protein 2; RNA polymerase II-associated factor 1 homolog
基因别名: F23149_1; PAF1; PD2
UniProt ID: (Human) Q8N7H5
Entrez Gene ID: (Human) 54623
negative regulation of transcription from RNA polymerase II promoter
endodermal cell fate commitment
transcription elongation from RNA polymerase II promoter
mRNA polyadenylation
histone monoubiquitination
Wnt signaling pathway
nucleosome positioning
stem cell population maintenance
positive regulation of histone methylation
positive regulation of mRNA 3'-end processing
positive regulation of transcription elongation from RNA polymerase II promoter
histone H2B ubiquitination
protein localization to nucleus
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to lipopolysaccharide
