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Invitrogen
PAH Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-24843
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 132-161 amino acids from the central region of human PAH
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
200 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine and rat based on sequence homology.
靶标信息
PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: L-phenylalanine hydroxylase; PAH; Phe-4-monooxygenase; phenylalanine 4-monooxygenase; phenylalanine hydroxylase; Phenylalanine-4-hydroxylase; unnamed protein product
基因别名: AW106920; PAH; PH; PKU; PKU1
UniProt ID: (Mouse) P16331
Entrez Gene ID: (Human) 5053, (Mouse) 18478
monooxygenase activity
phenylalanine 4-monooxygenase activity
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
catalytic activity
oxidoreductase activity
amino acid binding
protein homodimerization activity
metal ion binding
cofactor binding
L-phenylalanine metabolic process
L-phenylalanine catabolic process
tyrosine biosynthetic process
metabolic process
aromatic amino acid family metabolic process
protein hydroxylation
pteridine-containing compound metabolic process
tetrahydrobiopterin metabolic process
oxidation-reduction process
cellular amino acid biosynthetic process
catecholamine biosynthetic process
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