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Immunogen sequence: MSDGFDRAPE QTRPLRAPPS SQDKIPQQNS ESAMAKPQVV VAPVLMSKLS VNAPEFYPSG YSSSYTESYE DGCEDYPTLS EYVQDFLNHL TEQPGSFETE IEQFAETLNG CVTTDDALQE LVELIYQQAT SIPNFSYMGA RLCNYLSHHL TISPQSGNFR QLLLQRCRTE YEVKDQAAKG DEVTRKRFHA FVLFLGELYL NLEIKGTNGQ VTRADILQVG LRELLNALFS NPMDDNLICA VKLLKLTGSV LEDAWKEKGK; Positive Samples: HeLa, HepG2, A-549, 293T, BT-474, Mouse liver, Mouse kidney, Mouse brain, Rat brain; Cellular Location: Cytoplasm
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PABC1-interacting protein 1; PABP-interacting protein 1; PAIP-1; poly(A)-binding protein-interacting protein 1; polyadenylate binding protein-interacting protein 1; Polyadenylate-binding protein-interacting protein 1
基因别名: PAIP-1; PAIP1
UniProt ID: (Human) Q9H074, (Mouse) Q8VE62
Entrez Gene ID: (Human) 10605, (Mouse) 218693, (Rat) 365684
分子生物学功能:
RNA metabolism protein
