FIGURE: 1 / 1
Immunogen sequence: MSDGFDRAPE QTRPLRAPPS SQDKIPQQNS ESAMAKPQVV VAPVLMSKLS VNAPEFYPSG YSSSYTESYE DGCEDYPTLS EYVQDFLNHL TEQPGSFETE IEQFAETLNG CVTTDDALQE LVELIYQQAT SIPNFSYMGA RLCNYLSHHL TISPQSGNFR QLLLQRCRTE YEVKDQAAKG DEVTRKRFHA FVLFLGELYL NLEIKGTNGQ VTRADILQVG LRELLNALFS NPMDDNLICA VKLLKLTGSV LEDAWKEKGK; Positive Samples: HeLa, HepG2, A-549, 293T, BT-474, Mouse liver, Mouse kidney, Mouse brain, Rat brain; Cellular Location: Cytoplasm
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Protein Aliases: PABC1-interacting protein 1; PABP-interacting protein 1; PAIP-1; poly(A)-binding protein-interacting protein 1; polyadenylate binding protein-interacting protein 1; Polyadenylate-binding protein-interacting protein 1
Gene Aliases: PAIP-1; PAIP1
Molecular Function: RNA metabolism protein