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Invitrogen

PAK1 Polyclonal Antibody

高级验证

This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.

查看其他24个PAK1抗体
说明书
实验方案
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说明书
实验方案
技术支持

产品信息

PA5-17798

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:1,000
-

免疫组化（石蜡） (IHC (P))

1:100
-

免疫沉淀 (IP)

1:50
-
产品规格

种属反应

Mouse, Non-human primate, Pig, Rat, Guinea pig, Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to the amino-terminus of human PAK1
查看免疫原

偶联物

Unconjugated

形式

Liquid

纯化类型

Antigen affinity chromatography

保存液

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

内含物

no preservative

保存条件

-20°C

RRID

AB_10999945

产品详细信息

It is not recommended to aliquot this antibody.

This antibody is not cross-reactive with PAK2, PAK3 or other PAK family members.

靶标信息

PAK1 is a serine/threonine kinase that is a target for restenosis, cancer, and immunosuppression treatment. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: activated protein kinase alpha; ADRB2; alpha pak; Alpha-PAK; CDC42/RAC effector kinase PAK-A; EC 2.7.11.1; kinase PAK1; MGC130000; MGC130001; p21 (CDKN1A)-activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 1; p21-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p65-PAK; p68-PAK; PAK 1; PAK-1; PAK1B; Protein kinase MUK2; Serine/threonine-protein kinase PAK 1; STE20 homolog, yeast

基因别名: AW045634; PAK-1; PAK1; Paka; PAKalpha

UniProt ID: (Human) Q13153, (Rat) P35465

Entrez Gene ID: (Pig) 100525766, (Human) 5058, (Mouse) 18479, (Guinea pig) 100714662, (Rat) 29431

功能
response to hypoxia positive regulation of protein phosphorylation protein phosphorylation exocytosis apoptotic process Rho protein signal transduction regulation of mitotic cell cycle neuromuscular junction development metabolic process response to organic substance regulation of gene expression phosphorylation dendrite development cell migration amygdala development signal transduction by protein phosphorylation actin cytoskeleton organization stress-activated protein kinase signaling cascade actin cytoskeleton reorganization activation of protein kinase activity cellular response to insulin stimulus regulation of actin cytoskeleton organization positive regulation of peptidyl-serine phosphorylation positive regulation of intracellular estrogen receptor signaling pathway wound healing regulation of apoptotic process receptor clustering regulation of MAPK cascade positive regulation of JUN kinase activity protein autophosphorylation branching morphogenesis of an epithelial tube neuron projection morphogenesis positive regulation of stress fiber assembly negative regulation of cell proliferation involved in contact inhibition dendritic spine development gamma-aminobutyric acid secretion, neurotransmission glutamate secretion, neurotransmission cellular response to organic cyclic compound observational learning regulation of long-term synaptic potentiation MAPK cascade mitotic cell cycle stimulatory C-type lectin receptor signaling pathway axonogenesis positive regulation of cell proliferation positive regulation of cell migration T cell costimulation Fc-epsilon receptor signaling pathway Fc-gamma receptor signaling pathway involved in phagocytosis ephrin receptor signaling pathway T cell receptor signaling pathway activation of MAPKK activity small GTPase mediated signal transduction intracellular signal transduction
参与通路
protein kinase activity protein serine/threonine kinase activity receptor signaling protein serine/threonine kinase activity protein binding collagen binding ATP binding protein kinase binding nucleotide binding catalytic activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups Rac GTPase binding MAP kinase kinase kinase activity
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性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

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