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Invitrogen
PARN Polyclonal Antibody
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PARN Antibody (PA5-19552) in WB
Western blot analysis of Jurkat Whole Cell Lysate using Product # PA5-19552, PARN primary antibody at a dilution of 1 µg/mL (lane 1). Staining of A431 Whole Cell Lysate at a dilution of 1 µg/mL (lane 2). Blot treated with a secondary IR Dye680-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:10000.
产品信息
PA5-19552
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH derived from within residues 500 - 600 of Human PARN.
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA5-19552 targets PARN in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-19552 immunogen is synthetic peptide conjugated to KLH derived from within residues 500 - 600 of Human PARN.
PA5-19552 detects PARN which has a predicted molecular weight of approximately 75 kDa.
靶标信息
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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