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Invitrogen
PC4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-117086
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human SUB1 (NP_0067043)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.11 mg/mL
规格
111 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: HL-60, BT-474, SW620, Jurkat, Mouse brain
Immunogen sequence: MPKSKELVSS SSSGSDSDSE VDKKLKRKKQ VAPEKPVKKQ KTGETSRALS SSKQSSSSRD DNMFQIGKMR YVSVRDFKGK VLIDIREYWM DPEGEMKPGR KGISLNPEQW SQLKEQISDI DDAVRKL
靶标信息
PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activated RNA polymerase II transcription cofactor 4; p14; PC4; positive cofactor 4; RNA polymerase II transcriptional coactivator; single stranded DNA binding protein p9 precursor; single-stranded DNA-binding protein p9; SUB1 homolog, transcriptional regulator; TIS7; unnamed protein product
基因别名: p14; P15; P9; PC4; Rpo2tc1
UniProt ID: (Human) P53999, (Mouse) P11031
Entrez Gene ID: (Human) 10923, (Mouse) 20024
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