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Proteintech
PCDHGA1 Polyclonal Antibody
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产品信息
18279-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PCDHGA1 fusion protein Ag13107
偶联物
形式
Liquid
浓度
0.65 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: YSVPEETDKG SFVGNIAKDL GLQPQELADG GVRIVSRGRM PLFALNPRSG SLITARRIDR EELCAQSMPC LVSFNILVED KMKLFPVEVE IIDINDNTPQ FQLEELEFKM NEITTPGTRI SLPFGQDLDV GMNSLQSYQL SSNPHFSLDV QQGADGPQHP EMVLQSPLDR EEEAVHHLIL TASDGGEPVR SGTLRIYIQV VDANDNPPAF TQAQYHINVP ENVPLGTQLL MVNATDPDEG ANGEVTYSFH NVDHRVAQIF RLDSYTGEIS NKEPLDFEEY KMYSMEVQAQ DGAGLMAKVK VLIKVLDVND NAPEVTITS
靶标信息
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PCDH-gamma-A1; protocadherin gamma a1; Protocadherin gamma-A1
基因别名: PCDH-GAMMA-A1; PCDHGA1
UniProt ID: (Human) Q9Y5H4
Entrez Gene ID: (Human) 56114, (Mouse) 93709, (Rat) 553129
