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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PCGF1 Antibodies

          Invitrogen

          PCGF1 Polyclonal Antibody

          1个已发表图片
          1 篇参考文献
          查看其他4个PCGF1抗体
          说明书
          实验方案
          问题与答案
          技术支持
          说明书
          实验方案
          问题与答案
          技术支持

          Cite PCGF1 Polyclonal Antibody

          • 抗体检测数据 (1)
          • 已发表图片 (1)
          PCGF1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          PCGF1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          图: 1 / 2

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          PCGF1 Antibody (PA5-49390) in WB

          Western blot analysis of PCGF1 in lysates from human brain, mouse brain, mouse cerebellum, rat brain tissue (from left to right). Samples were incubated with PCGF1 polyclonal antibody (Product # PA5-49390) using a dilution of 1:1,000 followed by goat anti-rabbit IgG H&L (HRP) at a dilution of 1:10,000. Lysates at 20 µg per lane. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          PCGF1 Antibody in Western Blot (WB)
          PCGF1 Antibody in Western Blot (WB)

          产品信息

          PA5-49390

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:1,000
          查看1篇已发表文章 1篇已发表文章
          产品规格

          种属反应

          Human, Mouse, Rat

          已发表种属

          Not Applicable

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          KLH conjugated synthetic peptide between 117-151 amino acids from the Central region of human PCGF1.
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          0.5 mg/mL

          纯化类型

          Protein A, Antigen affinity chromatography

          保存液

          PBS, pH 7.4

          内含物

          0.09% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2634844

          产品详细信息

          Predicted to react with bovine based on sequence homology.

          靶标信息

          Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin- dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down- regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          生物信息学

          蛋白别名: nervous system polycomb 1; Nervous system Polycomb-1; NSPc1; Polycomb group RING finger protein 1; RING finger protein 68

          查看更多 收起

          基因别名: 2010002K04Rik; AU024121; NSPC1; PCGF1; RNF3A-2; RNF68

          查看更多 收起

          UniProt ID: (Human) Q9BSM1, (Mouse) Q8R023, (Rat) Q6DLV9

          查看更多 收起

          Entrez Gene ID: (Human) 84759, (Mouse) 69837, (Rat) 312480

          查看更多 收起

          功能
          protein binding protein C-terminus binding zinc ion binding metal ion binding molecular_function
          参与通路
          transcription, DNA-templated regulation of transcription, DNA-templated histone H2A monoubiquitination aging
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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