Abnova

PCID2 Polyclonal Antibody, MaxPab™

Name: PCID2 Polyclonal Antibody, MaxPab\u2122
Brand: Abnova
SKU: H00055795-D01P

查看其他7个PCID2抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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PCID2 Antibody (H00055795-D01P) in WB

Western Blot analysis of PCID2 expression in transfected 293T cell line by PCID2 MaxPab polyclonal antibody. Lane 1: PCID2 transfected lysate(45.80 KDa). Lane 2: Non-transfected lysate. .

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产品信息

H00055795-D01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

免疫细胞化学 (ICC/IF)

10-100 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

PCID2 (AAH31246.1, 1 a.a. approximately 397 a.a) full-length human protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MRLTDVVQQL VYEAIDSRDG ASCAELVSFK HPHVANPRLQ MASPEEKCQQ VLEPPYDEMF AAHLRCTYAV GDHDFIEAYK CQTVIVQSFL RAFQAHKEEN WALPVMYAVA LDLRVFANNA DQQLVKKGKS KVGDMLEKAA ELLMSCFRVC ASDTRAGIED SKKWGMLFLV NQLFKIYFKI NKLHLCKPLI RAIDSSNLKD DYSTAQRVTY KYYVGRKAMF DSDFKQAEEY LSFAFEHCHR SSQKNKRMIL IYLLPVKMLL GHMPTVELLK KYHLMQFAEV TRAVSEGNLL LLHEALAKHE AFFIRCGIFL ILEKLKIITY RNLFKKVYLL LKTHQLSLDA FLVALKFMQV EDVDIDEVQC ILANLIYMGH VKGYISHQHQ KLVVSKQNPF PPLSTVC

靶标信息

Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。