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Invitrogen
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Highest antigen sequence identity to the following orthologs: Mouse- 99%, Rat- 96%.
Sequence of this protein is as follows: LDKYNCDFCV HGNDITLTVD GRDTYEEVKQ AGRYRECKRT QGVSTTDLVG RMLLVTKAHH SSQEMSSEYR EYADSFGKCP G
ECT (ethanolaminephosphate cytidyltransferase) is an important regulatory enzyme in the pathway for phosphatidylethanolamine (PE) biosynthesis. PE functions in cell signalling, membrane fusion, platelet activation, and cell cycle progression. Specialized forms of PE exist as plasmologens, natural cannabinoid anadimade, and glycosylated PE. The ECT enzyme acts in the second of three catalysis steps to produce CDP-ethanolamine from phosphoethanolamine (P-Etn). Study of ECT could help determine the role of plasmologens in disease, specifically lipid disorders such as peroxisomal diseases as well as neuronal degeneration associated with Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CTP:phopshoethanolamine cytidylyltransferase; CTP:phosphoethanolamine cytidylyltransferase; Ethanolamine-phosphate cytidylyltransferase; PCYT2; Phosphorylethanolamine transferase; unnamed protein product
基因别名: ET; PCYT2; SPG82
UniProt ID: (Human) Q99447, (Rat) O88637
Entrez Gene ID: (Human) 5833, (Rat) 89841