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Invitrogen
PCYT2 Polyclonal Antibody
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产品信息
PA5150683
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.8 mg/mL
规格
80 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Highest antigen sequence identity to the following orthologs: Mouse- 86%, Rat- 87%.
Sequence of this protein is as follows: TAELLSHFKV DLVCHGKTEI IPDRDGSDPY QEPKRRGIFR QIDSGSNLTT DLIVQRIITN RLEYEARNQK KEAKELAFLE AARQQAAQPL GERDGDF
靶标信息
ECT (ethanolaminephosphate cytidyltransferase) is an important regulatory enzyme in the pathway for phosphatidylethanolamine (PE) biosynthesis. PE functions in cell signalling, membrane fusion, platelet activation, and cell cycle progression. Specialized forms of PE exist as plasmologens, natural cannabinoid anadimade, and glycosylated PE. The ECT enzyme acts in the second of three catalysis steps to produce CDP-ethanolamine from phosphoethanolamine (P-Etn). Study of ECT could help determine the role of plasmologens in disease, specifically lipid disorders such as peroxisomal diseases as well as neuronal degeneration associated with Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CTP:phosphoethanolamine cytidylyltransferase; Ethanolamine-phosphate cytidylyltransferase; PCYT2; Phosphorylethanolamine transferase; unnamed protein product
基因别名: ET; PCYT2; SPG82
UniProt ID: (Human) Q99447
Entrez Gene ID: (Human) 5833
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