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Invitrogen
PDDC1 Polyclonal Antibody
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产品信息
PA5-52613
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KPICAVGHGV AALCCATNED RSWVFDSYSL TGPSVCELVR APGFARLPLV VEDFVKDSGA CFSASEPDAV HVVLDRHLVT GQNASSTVPA VQNLLFLCGS RK
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 90%.
靶标信息
The PDDC1 (Parkinson Disease 7 Domain Containing 1) gene encodes a protein that is part of the DJ-1 protein family, known for its role in protecting cells against oxidative stress and neurodegenerative conditions. PDDC1 has been implicated in various cellular processes such as transcription regulation, response to oxidative damage, and cellular homeostasis. It is located on human chromosome 12 and is expressed in several tissues, including the brain. Although its exact function remains to be fully elucidated, PDDC1 shares homology with Parkinson's disease-associated protein DJ-1, suggesting a potential role in neuroprotection. Research indicates that PDDC1 might be involved in neural development and survival, and its dysregulation could contribute to diseases involving oxidative stress and neurodegeneration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ferry endosomal RAB5 effector complex subunit 5; Fy-5; Glutamine amidotransferase-like class 1 domain-containing protein 1; Parkinson disease 7 domain-containing protein 1
基因别名: FERRY5; GATD1; PDDC1
UniProt ID: (Human) Q8NB37
Entrez Gene ID: (Human) 347862
